Interesting facts

The selection of the risk genes

How are the genes selected?

The scientific literature already identifies a large number of genes that are associated with diseases, but in many cases, it was not possible to scientifically verify these associations. In other cases, although a significant statistical link exists, the influence of a possible genetic defect on the disease risk is too low to justify a genetic analysis only for precautionary purposes. After a rigorous selection of the potential risk genes, there remain, for example, 16 possible genes left connected with thrombosis. In each of these genes, several defects have already been discovered; these defects were linked with the increased risk of thrombosis, based on scientific studies conducted in collaboration with thrombosis patients.

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From these genes, only those genes were selected, which carry sufficient genetic defects in the European population to warrant genetic testing. Genes that, for example, trigger a defect in only one of 20,000 people, were deliberately not included in our program, because they cannot justify a genetic testing. It was also checked, for each gene, whether genetic defects in these genes also sufficiently increase the risk to justify such an action.

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